The reverse transcriptase also has ribonuclease activity that degrades the viral RNA during the synthesis of cDNA, along with DNA-dependent DNA polymerase activity that results in a sense DNA through the antisense cDNA.[sixty nine] Jointly, the cDNA and its complement variety a double-stranded viral DNA which is then transported into https://hivhub.in/hiv-epidemic-in-india-trends-and-state-wise-distribution/