If a dad or mum of your proband is understood to provide the pathogenic variant discovered from the proband, the chance for the sibs of inheriting the pathogenic variant is 50%. Due to reduced penetrance, sibs who inherit the pathogenic variant might or might not acquire aHUS (see Penetrance). Modular https://ahuhire84936.blog-ezine.com/32079457/facts-about-air-handling-unit-ahu-hire-revealed