Even though hemin breaking enzymes aren't yet present in plasmodium, it could be one reason why hemin binding accounts for parasite lysis (Ginsburg and Demel 1984). A different review indicates that drug-hemin elaborate binds to phospholipid levels therefore disrupting the respective membrane framework and producing mobile lysis (Ginsburg and Demel https://kylersirzg.blogocial.com/tetrahydrocannabinol-an-overview-68336884