Investigate into conolidine has resulted in discovery of an opioid receptor in your body called ACKR3/CXCR7. ACKR3 appears to be quite possibly the most wanted target for conolidine, which also disregards the other four classical opioid receptors(three). There exists interest in using conolidine for a pain-reliever based on proof https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers